Sutcliffe Research Group
Sutcliffe Research Group

Research Papers (2020 - current)

Guilty by Dissociation: Part B: Evaluation of Supercritical Fluid Chromatography (SFC-UV) for the analysis of regioisomeric diphenidine-derived Novel Psychoactive Substances (NPS). G Cochrane, JK Field, MC Hulme, N Gilbert, RE Mewis, MR Euerby and OB Sutcliffe, Journal of Pharmaceutical and Biomedical Analysis (2022).  Accepted (21st April 2022) [in-press].

 

Guilty by Dissociation: Part A: Development of a rapid Ultra-High Performance Liquid Chromatography (UHPLC)-MS/MS methodology for the analysis of regioisomeric diphenidine-derived Novel Psychoactive Substances (NPS), JK Field, C Hinz, CM Titman, MC Hulme, RM Cowan, JB Ainsworth-McMillan, N Gilbert, RJ Lee, J Marron, A Costello, RE Mewis, MR Euerby and OB Sutcliffe, Journal of Pharmaceutical and Biomedical Analysis (2022).  Accepted (21st April 2022) [in-press].

 

The metabolism of the synthetic cannabinoids ADB-BUTINACA and ADB-4en-PINACA and their detection in forensic toxicology casework and infused papers seized in prisons, R Kronstrand, C Norman, S Vikingsson, A Biemans, B Valencia Crespo, D Edwards, D Fletcher, N Gilbert, M Persson, R Reid, O Semenova, F Al Teneiji, X Wu, J Dahlén, N NicDaeid, F Tarbah, OB Sutcliffe, C McKenzie and H Gréen, Drug Testing and Analysis (2021), 1-19. DOI:10.1002/dta.3203.

 

Lab-on-a-Chip approaches for the detection of controlled drugs, including new psychoactive substances: A systematic review, L McNeill, D Megson, PE Linton, J Norrey, L Bradley, OB Sutcliffe and KJ Shaw, Forensic Chemistry (2021), 26, 100370.


Synthesis, characterisation, detection and quantification of a novel hexyl-substituted synthetic cannabinoid receptor agonist: (S)-N-(1-amino-3,3-dimethyl-1-oxobutan-2-yl)-1-hexyl-1H-indazole-3-carboxamide (ADB-HINACA), N Gilbert, A Costello, JR Ellison, U Khan, M Knight, MJ Linnell, R Ralphs, RE Mewis and OB Sutcliffe, Forensic Chemistry (2021), 26, 100354
 
The impact of the 2016 Psychoactive Substances Act on synthetic cannabinoid use within the homeless population: Markets, content and user harms, R Ralphs, P Gray and OB Sutcliffe, International J. Drug Policy (2021), 97, 103305.

 

Hyperpolarisation of Mirfentanil by SABRE in the presence of heroin, TBR Robertson, N Gilbert, OB Sutcliffe and RE Mewis, ChemPhysChem (2021), 22, 1059.

 

Detection, discrimination and quantification of amphetamine, cathinone and nor-ephedrine regioisomers using benchtop 1H- and 19F-NMR spectroscopy, MC Hulme, A Hayatbaksh, RM Brignall, N Gilbert, A Costello, CJ Schofield, DC Willamson, EK Kemsley, OB Sutcliffe and RE Mewis, Magn Reson Chem.  (2021), 1-10. https://doi.org/10.1002/mrc.5156

 

Fast & Fluorinated – Development and validation of a rapid benchtop NMR approach and other routine screening methods for the detection and quantification of synthesised fluorofentanyl derivatives, N Gilbert, RE Mewis and OB Sutcliffe, Forensic Chemistry (2021), 23, 100321.

 

Origami Chips: Development and validation of a paper-based Lab-on-a-Chip device for the rapid and cost-effective detection of 4-methylmethcathinone (mephedrone) and its metabolite, 4-methylephedrine in urine, L McNeill, C Pearson, D Megson, J Norrey, D Watson, D Ashworth, PE Linton, OB Sutcliffe and KJ Shaw, Forensic Chemistry (2021), 22, 100293.

 

Shape Matters: The application of activity-based in-vitro bioassays and chiral profiling to the pharmacological evaluation of synthetic cannabinoid receptor agonists in drug-infused papers seized in prisons, LH Antonides, A Cannaert, C Norman, N Nic Daeid, OB Sutcliffe, CP Stove and C McKenzie, Drug Testing and Analysis (2020), 1-16.

 

Classification of fentanyl analogues through principal component analysis (PCA) and hierarchical clustering of GC–MS data, N Gilbert, RE Mewis and OB Sutcliffe, Forensic Chemistry (2020), 21, 100287.

 

Quantification of MDMA in seized tablets using benchtop 1H NMR spectroscopy in the absence of internal standards, JH Hussain, N Gilbert, A Costello, CJ Schofield, EK Kemsley, OB Sutcliffe and RE Mewis, Forensic Chemistry (2020), 20, 100263.

 

Hitting the Jackpot - Development of Gas Chromatography-Mass Spectrometry (GC-MS) and other rapid screening methods for the analysis of 18 fentanyl-derived synthetic opioids, N Gilbert, LH Antonides, CJ Schofield, A Costello, B Kilkelly, AR Cain, PRV Dalziel, K Horner, RE Mewis and OB Sutcliffe, Drug Testing and Analysis (2020), 12, 798-811.

 

Benchtop NMR analysis of piperazine-based drugs hyperpolarised by SABRE, T Tennant, MC Hulme, TBR Robertson, OB Sutcliffe and RE Mewis, Magnetic Resonance in Chemistry (2020), 1–9.

 

Detection and quantification of synthetic cannabinoid receptor agonists in infused papers from prisons in a constantly evolving illicit market, C Norman, G Walker, B McKirdy, C McDonald, D Fletcher, LH Antonides, OB Sutcliffe, N Nic Daeid and C McKenzie, Drug Testing and Analysis (2020), 12, 538–554.

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© Oliver Sutcliffe