MANchester DRug Analysis & Knowledge Exchange (MANDRAKE) is research-active and publishes its findings - including the identification of novel substances, innovative methods for both lab and field detection and the biological/toxicological evauation of substances of concern in numerous internationally-recognised peer-reviewed journals. These outputs are presented below:
Rapid Detection and Quantification of Novel Psychoactive Substances (NPS) Using Raman Spectroscopy and Surface-Enhanced Raman Scattering, H Muhamadali, A Watt, Y Xu, M Chisanga, A Subaihi, C Jones, DI Ellis, OB Sutcliffe and R Goodacre, Front. Chem. (2019), 7, 412.
Enantiospecific Synthesis, Chiral Separation, and Biological Activity of Four Indazole-3-Carboxamide-Type Synthetic Cannabinoid Receptor Agonists and Their Detection in Seized Drug Samples, LH Antonides, A Cannaert, C Norman, L Vives, A Harrison, A Costello, N Nic Daeid, CP Stove, OB Sutcliffe and C McKenzie, Front. Chem. (2019), 7, 321.
Rapid Identification of Novel Psychoactive and Other Controlled Substances Using Low-Field 1H NMR Spectroscopy, LH Antonides, RM Brignall, A Costello, J Ellison, SE Firth, N Gilbert, BJ Groom, SJ Hudson, MC Hulme, J Marron, ZA Pullen, TBR Robertson, CJ Schofield, DC Williamson, EK Kemsley, OB Sutcliffe and RE Mewis, ACS Omega (2019), 4 (4), 7103-7112.
Analytical determination of heroin, fentanyl and fentalogues using high-performance liquid chromatography with diode array and amperometric detection, Hadil M. Elbardisy, CW Foster, L Cumba, LH Antonides, N Gilbert, CJ Schofield, TS Belal, W Talaat, OB Sutcliffe, HG Daabees and CE Banks, Analytical Methods (2019), 11, 1053-1063.
Forensic Electrochemistry: The Electroanalytical Sensing of Mephedrone Metabolites, HM Elbardisy, A García-Miranda Ferrari, CW Foster, OB Sutcliffe, DAC Brownson, TS Belal, W Talaat, HG Daabees and CE Banks, ACS Omega (2019), 4 (1), 1947–1954.
Engineering molecularly imprinted polymers (MIPs) for the selective extraction and quantification of the novel psychoactive substance (NPS) methoxphenidine and its regioisomers, JW Lowdon, SMO Alkirkit, RE Mewis, DA Fulton, CE Banks, OB Sutcliffe and M Peeters, Analyst (2018), 143, 2002-2007.
Chemical synthesis, characterisation and in vitro and in vivo metabolism of the synthetic opioid MT-45 and its newly identified fluorinated analogue 2F-MT-45 with metabolite confirmation in urine samples from known drug users, C McKenzie, OB Sutcliffe, KD Read, P Scullion, O Epemolu, D Fletcher, A Helander, O Beck, A Rylski, LH Antonides, J Riley, SA Smith and N Nic Daeid, Forensic Toxicology (2018), 36 (2), 359-374.
Chromatographic retention behaviour, modelling and optimization of a UHPLC-UV separation of the regioisomers of the Novel Psychoactive Substance (NPS) methoxphenidine (MXP), BO Boateng, M Fever, D Edwards, P Petersson, MR Euerby and OB Sutcliffe, Journal of Pharmaceutical and Biomedical Analysis (2018), 153, 238-247.